Sam Harris speaks with Michael Osterholm about his new book, The Big One: How We Must Prepare for Future Deadly Pandemics. They discuss the lessons learned from the COVID-19 pandemic, the major mistakes made in the public health response—including lockdowns, school closures, and border policies—the science of airborne versus droplet transmission, the pr…
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Making Sense #436 - A Crisis of Trust
A Conversation with Michael Osterholm
Oct 04, 2025
∙ Paid
Making Sense Podcast
Join neuroscientist, philosopher, and five-time New York Times best-selling author Sam Harris as he explores important and controversial questions about the mind, society, current events, moral philosophy, religion, and rationality—with an overarching focus on how a growing understanding of ourselves and the world is changing our sense of how we should live.
Sam is also the creator of the Waking Up app. Combining Sam’s decades of mindfulness practice, profound wisdom from varied philosophical and contemplative traditions, and a commitment to a secular, scientific worldview, Waking Up is a resource for anyone interested in living a more examined, fulfilling life—and a new operating system for the mind.
Waking Up offers free subscriptions to anyone who can’t afford one, and donates a minimum of 10% of profits to the most effective charities around the world. To learn more, please go to WakingUp.com.
Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA.
Join neuroscientist, philosopher, and five-time New York Times best-selling author Sam Harris as he explores important and controversial questions about the mind, society, current events, moral philosophy, religion, and rationality—with an overarching focus on how a growing understanding of ourselves and the world is changing our sense of how we should live.
Sam is also the creator of the Waking Up app. Combining Sam’s decades of mindfulness practice, profound wisdom from varied philosophical and contemplative traditions, and a commitment to a secular, scientific worldview, Waking Up is a resource for anyone interested in living a more examined, fulfilling life—and a new operating system for the mind.
Waking Up offers free subscriptions to anyone who can’t afford one, and donates a minimum of 10% of profits to the most effective charities around the world. To learn more, please go to WakingUp.com.
Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA.Listen on
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